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Utilizing split-NanoLuc luciferase fragments as luminescent probes for protein solubility in living cells

Protein misfolding and aggregation is now recognized as a hallmark of numerous human diseases. Standard bioanalytical techniques for monitoring protein aggregation generally rely on small molecules that provide an optical readout of fibril formation. While these methods have been useful for mechanis...

詳細記述

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書誌詳細
出版年:Methods Enzymol
主要な著者: Nelson, Travis J., Zhao, Jia, Stains, Cliff I.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567984/
https://ncbi.nlm.nih.gov/pubmed/31155065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.003
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