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Self-Assembling NanoLuc Luciferase Fragments as Probes for Protein Aggregation in Living Cells

Given the clear role of protein aggregation in human disease, there is a critical need for assays capable of quantifying protein aggregation in living systems. We hypothesized that the inherently low background and biocompatibility of luminescence signal readouts could provide a potential solution t...

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Publicat a:ACS Chem Biol
Autors principals: Zhao, Jia, Nelson, Travis J., Vu, Quyen, Truong, Tiffany, Stains, Cliff I.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110118/
https://ncbi.nlm.nih.gov/pubmed/26492083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00758
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