A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion

The Hippo pathway is an emerging signaling pathway that plays important roles in organ size control, tissue homeostasis, tumorigenesis, metastasis, drug resistance, and immune response. Although many regulators of the Hippo pathway have been reported, the extracellular stimuli and kinase regulators...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Nouri,, Kazem, Azad,, Taha, Lightbody, Elizabeth, Khanal, Prem, Nicol, Christopher J., Yang, Xiaolong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902680/
https://ncbi.nlm.nih.gov/pubmed/31431076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901343R
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