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Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs
Oct4 is widely considered the most important among the four Yamanaka reprogramming factors. Here, we show that the combination of Sox2, Klf4, and cMyc (SKM) suffices for reprogramming mouse somatic cells to induced pluripotent stem cells (iPSCs). Simultaneous induction of Sox2 and cMyc in fibroblast...
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| 出版年: | Cell Stem Cell |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900749/ https://ncbi.nlm.nih.gov/pubmed/31708402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.10.002 |
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