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Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal excitation and inhibition. Our understanding of the neurophysiological mechanisms that render the brain epileptogenic remains incomplete, reflected by...

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發表在:Front Cell Neurosci
Main Authors: Duy, Phan Q., David, Wyatt B., Kahle, Kristopher T.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873151/
https://ncbi.nlm.nih.gov/pubmed/31803025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00515
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