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Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal excitation and inhibition. Our understanding of the neurophysiological mechanisms that render the brain epileptogenic remains incomplete, reflected by...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Duy, Phan Q., David, Wyatt B., Kahle, Kristopher T.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873151/
https://ncbi.nlm.nih.gov/pubmed/31803025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00515
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