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Kinase-KCC2 coupling: Cl(−) rheostasis, disease susceptibility, therapeutic target

The intracellular concentration of Cl(−) ([Cl(−)](i)) in neurons is a highly regulated variable that is established and modulated by the finely tuned activity of the KCC2 cotransporter. Despite the importance of KCC2 for neurophysiology and its role in multiple neuropsychiatric diseases, our knowled...

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Détails bibliographiques
Publié dans:J Neurophysiol
Auteurs principaux: Kahle, Kristopher T., Delpire, Eric
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760510/
https://ncbi.nlm.nih.gov/pubmed/26510764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00865.2015
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