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Preclinical insights into therapeutic targeting of KCC2 for disorders of neuronal hyperexcitability

INTRODUCTION: Epilepsy is a common neurological disorder of neuronal hyperexcitability that begets recurrent and unprovoked seizures. The lack of a truly satisfactory pharmacotherapy for epilepsy highlights the clinical urgency for the discovery of new drug targets. To that end, targeting the electr...

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Dettagli Bibliografici
Pubblicato in:Expert Opin Ther Targets
Autori principali: Duy, Phan Q., He, Miao, He, Zhigang, Kahle, Kristopher T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104019/
https://ncbi.nlm.nih.gov/pubmed/32336175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2020.1762174
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