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A mutational signature in gastric cancer suggests therapeutic strategies
Targeting defects in the DNA repair machinery of neoplastic cells, for example, those due to inactivating BRCA1 and/or BRCA2 mutations, has been used for developing new therapies in certain types of breast, ovarian and pancreatic cancers. Recently, a mutational signature was associated with failure...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918743/ https://ncbi.nlm.nih.gov/pubmed/26511885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9683 |
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