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A mutational signature in gastric cancer suggests therapeutic strategies

Targeting defects in the DNA repair machinery of neoplastic cells, for example, those due to inactivating BRCA1 and/or BRCA2 mutations, has been used for developing new therapies in certain types of breast, ovarian and pancreatic cancers. Recently, a mutational signature was associated with failure...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Alexandrov, Ludmil B., Nik-Zainal, Serena, Siu, Hoi Cheong, Leung, Suet Yi, Stratton, Michael R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918743/
https://ncbi.nlm.nih.gov/pubmed/26511885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9683
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