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Mutational Signatures in Breast Cancer: The Problem at the DNA Level

A breast cancer genome is a record of the historic mutagenic activity that has occurred throughout the development of the tumour. Indeed, every mutation may be informative. While driver mutations were the main focus of cancer research for a long time, passenger mutational signatures, the imprints of...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Nik-Zainal, Serena, Morganella, Sandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458139/
https://ncbi.nlm.nih.gov/pubmed/28572256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2810
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