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Mutational Signatures in Breast Cancer: The Problem at the DNA Level

A breast cancer genome is a record of the historic mutagenic activity that has occurred throughout the development of the tumour. Indeed, every mutation may be informative. While driver mutations were the main focus of cancer research for a long time, passenger mutational signatures, the imprints of...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Principais autores: Nik-Zainal, Serena, Morganella, Sandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458139/
https://ncbi.nlm.nih.gov/pubmed/28572256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2810
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