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Mutational Signatures in Breast Cancer: The Problem at the DNA Level

A breast cancer genome is a record of the historic mutagenic activity that has occurred throughout the development of the tumour. Indeed, every mutation may be informative. While driver mutations were the main focus of cancer research for a long time, passenger mutational signatures, the imprints of...

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Publicat a:Clin Cancer Res
Autors principals: Nik-Zainal, Serena, Morganella, Sandro
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458139/
https://ncbi.nlm.nih.gov/pubmed/28572256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2810
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