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A mutational signature in gastric cancer suggests therapeutic strategies

Targeting defects in the DNA repair machinery of neoplastic cells, for example, those due to inactivating BRCA1 and/or BRCA2 mutations, has been used for developing new therapies in certain types of breast, ovarian and pancreatic cancers. Recently, a mutational signature was associated with failure...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Alexandrov, Ludmil B., Nik-Zainal, Serena, Siu, Hoi Cheong, Leung, Suet Yi, Stratton, Michael R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918743/
https://ncbi.nlm.nih.gov/pubmed/26511885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9683
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