Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal excitation and inhibition. Our understanding of the neurophysiological mechanisms that render the brain epileptogenic remains incomplete, reflected by...

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Publicat a:Front Cell Neurosci
Autors principals: Duy, Phan Q., David, Wyatt B., Kahle, Kristopher T.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Cellular Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873151/
https://ncbi.nlm.nih.gov/pubmed/31803025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00515
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