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Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells

BACKGROUND & AIMS: Methyl-CpG binding protein 2, MECP2, which binds to methylated regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for development of liver fibrosis in mice. We investigated the effects of MECP2 deletion from HSCs on their tr...

詳細記述

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書誌詳細
出版年:Gastroenterology
主要な著者: Moran-Salvador, Eva, Garcia-Macia, Marina, Sivaharan, Ashwin, Sabater, Laura, Zaki, Marco Y.W., Oakley, Fiona, Knox, Amber, Page, Agata, Luli, Saimir, Mann, Jelena, Mann, Derek A.
フォーマット: Artigo
言語:Inglês
出版事項: W.B. Saunders 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853276/
https://ncbi.nlm.nih.gov/pubmed/31352003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.07.029
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