Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells

BACKGROUND & AIMS: Methyl-CpG binding protein 2, MECP2, which binds to methylated regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for development of liver fibrosis in mice. We investigated the effects of MECP2 deletion from HSCs on their tr...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Gastroenterology
Glavni autori: Moran-Salvador, Eva, Garcia-Macia, Marina, Sivaharan, Ashwin, Sabater, Laura, Zaki, Marco Y.W., Oakley, Fiona, Knox, Amber, Page, Agata, Luli, Saimir, Mann, Jelena, Mann, Derek A.
Format: Artigo
Jezik:Inglês
Izdano: W.B. Saunders 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853276/
https://ncbi.nlm.nih.gov/pubmed/31352003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.07.029
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items