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CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection
CSB, a member of the SWI2/SNF2 superfamily, has been implicated in evicting histones to promote the DSB pathway choice towards homologous recombination (HR) repair. However, how CSB promotes HR repair remains poorly characterized. Here we demonstrate that CSB interacts with both MRE11/RAD50/NBS1 (MR...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6847465/ https://ncbi.nlm.nih.gov/pubmed/31501894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz784 |
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