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CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection

CSB, a member of the SWI2/SNF2 superfamily, has been implicated in evicting histones to promote the DSB pathway choice towards homologous recombination (HR) repair. However, how CSB promotes HR repair remains poorly characterized. Here we demonstrate that CSB interacts with both MRE11/RAD50/NBS1 (MR...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Batenburg, Nicole L, Walker, John R, Coulombe, Yan, Sherker, Alana, Masson, Jean-Yves, Zhu, Xu-Dong
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847465/
https://ncbi.nlm.nih.gov/pubmed/31501894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz784
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