Human CtIP promotes DNA end resection

In the S and G2 phases of the cell cycle, DNA double-strand breaks (DSBs) are processed into single-stranded DNA, triggering ATR-dependent checkpoint signaling and DSB repair by homologous recombination (HR). Previous work has implicated the MRE11 complex in such DSB processing events. Here, we show...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sartori, Alessandro A., Lukas, Claudia, Coates, Julia, Mistrik, Martin, Fu, Shuang, Bartek, Jiri, Baer, Richard, Lukas, Jiri, Jackson, Stephen P.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409435/
https://ncbi.nlm.nih.gov/pubmed/17965729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06337
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