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The DNA resection protein CtIP promotes mammary tumorigenesis

Many DNA repair factors act to suppress tumor formation by preserving genomic stability. Similarly, the CtIP protein, which interacts with the BRCA1 tumor suppressor, is also thought to have tumor suppression activity. Through its role in DNA end resection, CtIP facilitates DNA double-strand break (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Reczek, Colleen R., Shakya, Reena, Miteva, Yana, Szabolcs, Matthias, Ludwig, Thomas, Baer, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078005/
https://ncbi.nlm.nih.gov/pubmed/27058754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8605
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