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The DNA resection protein CtIP promotes mammary tumorigenesis

Many DNA repair factors act to suppress tumor formation by preserving genomic stability. Similarly, the CtIP protein, which interacts with the BRCA1 tumor suppressor, is also thought to have tumor suppression activity. Through its role in DNA end resection, CtIP facilitates DNA double-strand break (...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Reczek, Colleen R., Shakya, Reena, Miteva, Yana, Szabolcs, Matthias, Ludwig, Thomas, Baer, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078005/
https://ncbi.nlm.nih.gov/pubmed/27058754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8605
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