PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES

Tryptophan is an essential amino-acid broken down initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Additional tryptophan metabolites include...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Innov Aging
Hauptverfasser: Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Session 830 (Poster)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845321/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.375
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