PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES

Tryptophan is an essential amino-acid broken down initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Additional tryptophan metabolites include...

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Detalles Bibliográficos
Publicado en:Innov Aging
Main Authors: Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Session 830 (Poster)
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845321/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.375
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