Kynurenine, a Tryptophan Metabolite that Accumulates with Age, Induces Bone Loss

Age-dependent bone loss occurs in humans and in several animal species, including rodents. The underlying causal mechanisms are probably multifactorial, although an age-associated increase in the generation of reactive oxygen species has been frequently implicated. We previously reported that aromat...

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Pubblicato in:J Bone Miner Res
Autori principali: El Refaey, Mona, McGee-Lawrence, Meghan E., Fulzele, Sadanand, Kennedy, Eileen J., Bollag, Wendy B., Elsalanty, Mohammed, Zhong, Qing, Ding, Ke-Hong, Bendzunas, Nathaniel G., Shi, Xing-ming, Xu, Jianrui, Hill, William D., Johnson, Maribeth H., Hunter, Monte, Pierce, Jessica L., Yu, Kanglun, Hamrick, Mark W., Isales, Carlos M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685888/
https://ncbi.nlm.nih.gov/pubmed/28727234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3224
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