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KYNURENIC ACID A TRYPTOPHAN METABOLITE INDUCES BONE LOSS IN MICE
The generation of reactive oxygen species increases with age and may play a pathogenic role in the development of osteoporosis. We previously reported that kynurenine (kyn), the initial metabolite in tryptophan oxidation, accumulates with age and feeding kyn to younger mice results in an accelerated...
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| Publicado en: | Innov Aging |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230057/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.377 |
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