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KYNURENIC ACID A TRYPTOPHAN METABOLITE INDUCES BONE LOSS IN MICE

The generation of reactive oxygen species increases with age and may play a pathogenic role in the development of osteoporosis. We previously reported that kynurenine (kyn), the initial metabolite in tryptophan oxidation, accumulates with age and feeding kyn to younger mice results in an accelerated...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Isales, C, Ding, K, Bollag, W, McGee-Lawrence, M, Hill, W, Shi, X, Elsalanty, M, Hamrick, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230057/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.377
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