PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES

Tryptophan is an essential amino-acid broken down initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Additional tryptophan metabolites include...

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Vydáno v:Innov Aging
Hlavní autoři: Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Session 830 (Poster)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845321/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.375
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