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PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES

Tryptophan is an essential amino-acid broken down initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Additional tryptophan metabolites include...

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Dettagli Bibliografici
Pubblicato in:Innov Aging
Autori principali: Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845321/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.375
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