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Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

BACKGROUND: Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. METHODS: Necro...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Wang, Yiwei, Zhao, Minghui, He, Sijia, Luo, Yuntao, Zhao, Yucui, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Liu, Xinjian, Li, Chuanyuan, Huang, Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842489/
https://ncbi.nlm.nih.gov/pubmed/31706322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1423-5
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