Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE(2) pathway in non-small cell lung cancer

Radiotherapy is an effective treatment for non-small cell lung cancer (NSCLC). However, irradiated, dying tumor cells generate potent growth stimulatory signals during radiotherapy that promote the repopulation of adjacent surviving tumor cells to cause tumor recurrence. We investigated the function...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhao, Minghui, Wang, Yiwei, Zhao, Yucui, He, Sijia, Zhao, Ruyi, Song, Yanwei, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Huang, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695367/
https://ncbi.nlm.nih.gov/pubmed/33180744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103984
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