Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE(2) pathway in non-small cell lung cancer

Radiotherapy is an effective treatment for non-small cell lung cancer (NSCLC). However, irradiated, dying tumor cells generate potent growth stimulatory signals during radiotherapy that promote the repopulation of adjacent surviving tumor cells to cause tumor recurrence. We investigated the function...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Zhao, Minghui, Wang, Yiwei, Zhao, Yucui, He, Sijia, Zhao, Ruyi, Song, Yanwei, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Huang, Qian
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695367/
https://ncbi.nlm.nih.gov/pubmed/33180744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103984
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