Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

Cancer stem cells (CSCs) are a sub-population of tumor cells playing essential roles in initiation, differentiation, recurrence, metastasis and development of drug resistance of various cancers, including bladder cancer. Although multiple lines of evidence suggest that metformin is capable of repres...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Liu, Qiuli, Yuan, Wenqiang, Tong, Dali, Liu, Gaolei, Lan, Weihua, Zhang, Dianzheng, Xiao, Hualiang, Zhang, Yao, Huang, Zaoming, Yang, Junjie, Zhang, Jun, Jiang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053723/
https://ncbi.nlm.nih.gov/pubmed/27058422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8595
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