Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

Cancer stem cells (CSCs) are a sub-population of tumor cells playing essential roles in initiation, differentiation, recurrence, metastasis and development of drug resistance of various cancers, including bladder cancer. Although multiple lines of evidence suggest that metformin is capable of repres...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Qiuli, Yuan, Wenqiang, Tong, Dali, Liu, Gaolei, Lan, Weihua, Zhang, Dianzheng, Xiao, Hualiang, Zhang, Yao, Huang, Zaoming, Yang, Junjie, Zhang, Jun, Jiang, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053723/
https://ncbi.nlm.nih.gov/pubmed/27058422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8595
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