Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

Abstract Background Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. Method...

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Detalhes bibliográficos
Main Authors: Yiwei Wang, Minghui Zhao, Sijia He, Yuntao Luo, Yucui Zhao, Jin Cheng, Yanping Gong, Jianzhu Xie, Yulan Wang, Binjie Hu, Ling Tian, Xinjian Liu, Chuanyuan Li, Qian Huang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-11-01
Colecção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Radiotherapy
Necroptosis
Tumor repopulation
RIP1/RIP3/MLKL/JNK/IL-8 pathway
Acesso em linha:http://link.springer.com/article/10.1186/s13046-019-1423-5
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