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Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
Mixed lineage kinase domain-like protein (Mlkl) was recently found to interact with receptor interacting protein 3 (Rip3) and to be essential for tumor necrosis factor (TNF)-induced programmed necrosis (necroptosis) in cultured cell lines. We have generated Mlkl-deficient mice by transcription activ...
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731568/ https://ncbi.nlm.nih.gov/pubmed/23835476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.91 |
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