Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

Mixed lineage kinase domain-like protein (Mlkl) was recently found to interact with receptor interacting protein 3 (Rip3) and to be essential for tumor necrosis factor (TNF)-induced programmed necrosis (necroptosis) in cultured cell lines. We have generated Mlkl-deficient mice by transcription activ...

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Detalhes bibliográficos
Main Authors: Wu, Jianfeng, Huang, Zhe, Ren, Junming, Zhang, Zhirong, He, Peng, Li, Yangxin, Ma, Jianhui, Chen, Wanze, Zhang, Yingying, Zhou, Xiaojuan, Yang, Zhentao, Wu, Su-Qin, Chen, Lanfen, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731568/
https://ncbi.nlm.nih.gov/pubmed/23835476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.91
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