Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

BACKGROUND: Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. METHODS: Necro...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Wang, Yiwei, Zhao, Minghui, He, Sijia, Luo, Yuntao, Zhao, Yucui, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Liu, Xinjian, Li, Chuanyuan, Huang, Qian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842489/
https://ncbi.nlm.nih.gov/pubmed/31706322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1423-5
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