RIP1/RIP3/MLKL-mediated necroptosis contributes to vinblastine-induced myocardial damage

Vinblastine (VBL) has been considered as a first-line anti-tumor drug for many years. However, vinblastine-caused myocardial damage has been continually reported. The underlying molecular mechanism of the myocardial damage remains unknown. Here, we show that vinblastine induces myocardial damage and...

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Udgivet i:Mol Cell Biochem
Main Authors: Zhou, Huiling, Liu, Lijun, Ma, Xiaolong, Wang, Jian, Yang, Jinfu, Zhou, Xinmin, Yang, Yifeng, Liu, Haidan
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873015/
https://ncbi.nlm.nih.gov/pubmed/33247805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-020-03985-3
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