Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy

Chemotherapy can reinstate anticancer immunosurveillance through inducing tumor immunogenic cell death (ICD). Here, we show that anthracyclines and oxaliplatin can trigger necroptosis in murine cancer cell lines expressing receptor-interacting serine-threonine kinase 3 (RIP3) and mixed lineage kinas...

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Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Yang, Heng, Ma, Yuting, Chen, Guo, Zhou, Heng, Yamazaki, Takahiro, Klein, Christophe, Pietrocola, Federico, Vacchelli, Erika, Souquere, Sylvie, Sauvat, Allan, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938314/
https://ncbi.nlm.nih.gov/pubmed/27471616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1149673
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