Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy

Chemotherapy can reinstate anticancer immunosurveillance through inducing tumor immunogenic cell death (ICD). Here, we show that anthracyclines and oxaliplatin can trigger necroptosis in murine cancer cell lines expressing receptor-interacting serine-threonine kinase 3 (RIP3) and mixed lineage kinas...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Yang, Heng, Ma, Yuting, Chen, Guo, Zhou, Heng, Yamazaki, Takahiro, Klein, Christophe, Pietrocola, Federico, Vacchelli, Erika, Souquere, Sylvie, Sauvat, Allan, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938314/
https://ncbi.nlm.nih.gov/pubmed/27471616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1149673
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