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Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade

In preclinical in vivo models of cancer, the induction of immunogenic cell death (ICD) sensitizes to subsequent immunotherapy. Several clinical trials now confirm that pretreatment with ICD-inducing anthracyclines sensitizes to immune checkpoint blockade targeting PD-1 and PD-L1 interaction. These f...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Kepp, Oliver, Zitvogel, Laurence, Kroemer, Guido
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791413/
https://ncbi.nlm.nih.gov/pubmed/31646079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1637188
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