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Targeting PD-1/PD-L1 interactions for cancer immunotherapy

Tumors have developed multiple immunosuppressive mechanisms to turn down the innate and the effector arms of the immune system, thus compromising most of the immunotherapeutic strategies that have been proposed during the last decade. Right after the pioneering success of Ipilimumab (anti-CTLA4) in...

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Detalhes bibliográficos
Main Authors: Zitvogel, Laurence, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518493/
https://ncbi.nlm.nih.gov/pubmed/23243584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21335
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