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Can the exome and the immunome converge on the design of efficient cancer vaccines?
Human cancers carry hundreds of non-synonymous mutations, several dozens among which may lead to the generation of tumor-specific MHC Class I-restricted epitopes. Hence every patient’s tumor harbors a highly specific mutational and antigenic signature and up to 95% of these mutations are unique. Thi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429561/ https://ncbi.nlm.nih.gov/pubmed/22934249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20730 |
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