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Targeting PD-1/PD-L1 interactions for cancer immunotherapy

Tumors have developed multiple immunosuppressive mechanisms to turn down the innate and the effector arms of the immune system, thus compromising most of the immunotherapeutic strategies that have been proposed during the last decade. Right after the pioneering success of Ipilimumab (anti-CTLA4) in...

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Autors principals: Zitvogel, Laurence, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518493/
https://ncbi.nlm.nih.gov/pubmed/23243584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21335
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