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Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

BACKGROUND: Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. METHODS: Necro...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Wang, Yiwei, Zhao, Minghui, He, Sijia, Luo, Yuntao, Zhao, Yucui, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Liu, Xinjian, Li, Chuanyuan, Huang, Qian
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842489/
https://ncbi.nlm.nih.gov/pubmed/31706322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1423-5
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