Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

BACKGROUND: Tumor cell repopulation after radiotherapy is a major cause for the tumor radioresistance and recurrence. This study aims to investigate the underlying mechanism of tumor repopulation after radiotherapy, with focus on whether and how necroptosis takes part in this process. METHODS: Necro...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Wang, Yiwei, Zhao, Minghui, He, Sijia, Luo, Yuntao, Zhao, Yucui, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Liu, Xinjian, Li, Chuanyuan, Huang, Qian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842489/
https://ncbi.nlm.nih.gov/pubmed/31706322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1423-5
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