A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

We report a detailed structure–activity relationship for the scaffold of VUF16216, a compound we have previously communicated as a small-molecule efficacy photoswitch for the peptidergic chemokine GPCR CXCR3. A series of photoswitchable azobenzene ligands was prepared through various synthetic strat...

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Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Gómez-Santacana, Xavier, de Munnik, Sabrina M, Mocking, Tamara A M, Hauwert, Niels J, Sun, Shanliang, Vijayachandran, Prashanna, de Esch, Iwan J P, Vischer, Henry F, Wijtmans, Maikel, Leurs, Rob
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839561/
https://ncbi.nlm.nih.gov/pubmed/31728165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.244
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