HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

To investigate the possibility that HIV-1 replication in lymph nodes sustains the reservoir during antiretroviral therapy (ART), we looked for evidence of viral replication in 5 donors after up to 13 years of viral suppression. We characterized proviral populations in lymph nodes and peripheral bloo...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: McManus, William R., Bale, Michael J., Spindler, Jonathan, Wiegand, Ann, Musick, Andrew, Patro, Sean C., Sobolewski, Michele D., Musick, Victoria K., Anderson, Elizabeth M., Cyktor, Joshua C., Halvas, Elias K., Shao, Wei, Wells, Daria, Wu, Xiaolin, Keele, Brandon F., Milush, Jeffrey M., Hoh, Rebecca, Mellors, John W., Hughes, Stephen H., Deeks, Steven G., Coffin, John M., Kearney, Mary F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819093/
https://ncbi.nlm.nih.gov/pubmed/31361603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126714
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