HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

To investigate the possibility that HIV-1 replication in lymph nodes sustains the reservoir during antiretroviral therapy (ART), we looked for evidence of viral replication in 5 donors after up to 13 years of viral suppression. We characterized proviral populations in lymph nodes and peripheral bloo...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: McManus, William R., Bale, Michael J., Spindler, Jonathan, Wiegand, Ann, Musick, Andrew, Patro, Sean C., Sobolewski, Michele D., Musick, Victoria K., Anderson, Elizabeth M., Cyktor, Joshua C., Halvas, Elias K., Shao, Wei, Wells, Daria, Wu, Xiaolin, Keele, Brandon F., Milush, Jeffrey M., Hoh, Rebecca, Mellors, John W., Hughes, Stephen H., Deeks, Steven G., Coffin, John M., Kearney, Mary F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819093/
https://ncbi.nlm.nih.gov/pubmed/31361603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126714
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