HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

To investigate the possibility that HIV-1 replication in lymph nodes sustains the reservoir during antiretroviral therapy (ART), we looked for evidence of viral replication in 5 donors after up to 13 years of viral suppression. We characterized proviral populations in lymph nodes and peripheral bloo...

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Pubblicato in:J Clin Invest
Autori principali: McManus, William R., Bale, Michael J., Spindler, Jonathan, Wiegand, Ann, Musick, Andrew, Patro, Sean C., Sobolewski, Michele D., Musick, Victoria K., Anderson, Elizabeth M., Cyktor, Joshua C., Halvas, Elias K., Shao, Wei, Wells, Daria, Wu, Xiaolin, Keele, Brandon F., Milush, Jeffrey M., Hoh, Rebecca, Mellors, John W., Hughes, Stephen H., Deeks, Steven G., Coffin, John M., Kearney, Mary F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819093/
https://ncbi.nlm.nih.gov/pubmed/31361603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126714
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