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Heating during agitation of β(2)-microglobulin reveals that supersaturation breakdown is required for amyloid fibril formation at neutral pH
Amyloidosis-associated amyloid fibrils are formed by denatured proteins when supersaturation of denatured proteins is broken. β(2)-Microglobulin (β2m) forms amyloid fibrils and causes dialysis-related amyloidosis in patients receiving long-term hemodialysis. Although amyloid fibrils of β2m in patien...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816083/ https://ncbi.nlm.nih.gov/pubmed/31495783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009971 |
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