Possible mechanisms of polyphosphate-induced amyloid fibril formation of β(2)-microglobulin

Polyphosphate (polyP), which is found in various microorganisms and human cells, is an anionic biopolymer consisting of inorganic phosphates linked by high-energy phosphate bonds. Previous studies revealed that polyPs strongly promoted the amyloid formation of several amyloidogenic proteins; however...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Chun-ming, Yamaguchi, Keiichi, So, Masatomo, Sasahara, Kenji, Ito, Toru, Yamamoto, Suguru, Narita, Ichiei, Kardos, József, Naiki, Hironobu, Goto, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600944/
https://ncbi.nlm.nih.gov/pubmed/31182591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819813116
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