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Aggregation-phase diagrams of β(2)-microglobulin reveal temperature and salt effects on competitive formation of amyloids versus amorphous aggregates

Several serious diseases are associated with crystal-like amyloid fibrils or glass-like amorphous aggregates of denatured proteins. However, protein aggregation involving both types of aggregates has not yet been elucidated in much detail. Using a protein associated with dialysis-related amyloidosis...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Adachi, Masayuki, Noji, Masahiro, So, Masatomo, Sasahara, Kenji, Kardos, József, Naiki, Hironobu, Goto, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153281/
https://ncbi.nlm.nih.gov/pubmed/30077972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004683
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