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CRISPR-Cas12a Nucleases Bind Flexible DNA Duplexes without RNA/DNA Complementarity
[Image: see text] Cas12a (also known as “Cpf1”) is a class 2 type V-A CRISPR-associated nuclease that can cleave double-stranded DNA at specific sites. The Cas12a effector enzyme comprises a single protein and a CRISPR-encoded small RNA (crRNA) and has been used for genome editing and manipulation....
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| Wydane w: | ACS Omega |
|---|---|
| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2019
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811856/ https://ncbi.nlm.nih.gov/pubmed/31656887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01469 |
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