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Nucleic-acid dependent conformational changes in CRISPR-Cas9 revealed by site-directed spin labeling
In a type II Clustered-Regularly-Interspersed-Short-Palindromic-Repeats (CRISPR) system, RNAs derived from the CRISPR locus complex with the CRISPR-associated (Cas) protein Cas9 to form an RNA-guided nuclease that cleaves double-stranded DNAs at specific sites. In recent years, the CRISPR-Cas9 syste...
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| Publicado no: | Cell Biochem Biophys |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5183522/ https://ncbi.nlm.nih.gov/pubmed/27342128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-016-0738-5 |
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