A carregar...
CRISPR–Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling
The RNA-guided CRISPR–Cas9 nuclease has revolutionized genome engineering, yet its mechanism for DNA target selection is not fully understood. A crucial step in Cas9 target recognition involves unwinding of the DNA duplex to form a three-stranded R-loop structure. Work reported here demonstrates dir...
Na minha lista:
| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501335/ https://ncbi.nlm.nih.gov/pubmed/28437608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01137 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|