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The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies

Bacterial and archaeal CRISPR-Cas systems offer adaptive immune protection against foreign mobile genetic elements (MGEs). This function is regulated by sequence specific binding of CRISPR RNA (crRNA) to target DNA/RNA, with an additional requirement of a flanking DNA motif called the protospacer ad...

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Détails bibliographiques
Publié dans:Front Cell Infect Microbiol
Auteurs principaux: Newsom, Sydney, Parameshwaran, Hari Priya, Martin, Lindsie, Rajan, Rakhi
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876343/
https://ncbi.nlm.nih.gov/pubmed/33585286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.619763
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